Women are better able to cope with Covid-19 than men – VnExpress

AmericaThe female hormone estrogen helps women better cope with Covid-19, thereby reducing the risk of death, according to research published in the BMJ Open.

According to data from the US Centers for Disease Control and Prevention, the death rate for men from Covid-19 is 20% higher than that of women. The scientists hypothesized that the difference in risk between the sexes could be partly attributed to the role the hormone estrogen plays in the immune system.

New research published on BMJ Open 14, linking estrogen levels to women’s likelihood of dying after they were infected with Covid-19. Accordingly, the researchers looked at Swedish national health registry data from more than 16,000 women, aged 50-80, who had tested positive for Covid since February 4, 2022. until September 14, 2020. Most have gone through menopause, in which estrogen typically declines.

The researchers were particularly interested in women in the group who were taking medications that affect estrogen levels: 227 were on hormone therapy, a breast cancer treatment that lowers estrogen, and about 2,500 were undergoing treatment. Hormone replacement therapy, which increases estrogen levels to relieve menopausal symptoms. After adjusting for other risk factors, the scientists found that women who took extra estrogen had a 53 percent lower risk of dying from Covid-19 than women who did not receive the treatment.

Some studies suggest that the hormone estrogen may reduce the risk of dying from Covid-19 in women. Photo: SWHR

Dr Franck Mauvais – Jarvis, director of the Sex-Based Medicine Laboratory at Tulane University, said that estrogen and the hormone progesterone, to a lesser extent – are thought to be involved in the body’s immune response. and can reduce inflammation. During Covid-19, inflammation can cause a “cytokine storm,” a dangerous condition in which the immune system can become overwhelmed.

Dr Malin Sund, professor at Umea University in Sweden and study co-author, said that estrogen can also affect spike protein receptors, which SARS-CoV-2 – the virus that causes Covid -19 – used to enter cells.

However, as Sund and her authors point out, randomized clinical trials are needed to determine if the link is causal and if artificially increased estrogen could protect patients. from Covid-19.

Sund stresses that people should not experiment with changing their estrogen levels; Elevating estrogen levels can have side effects, such as an increased risk of breast cancer. “Conversely, women who already have breast cancer should absolutely not stop hormone therapy based on this study because they really need cancer treatment. The best they can do is get vaccinated,” Sud said. .

Equanimity (according to Time)


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