Vaccine Covid-19 Moderna has several advantages over Pfizer – VnExpress

AmericaThe Moderna vaccine is transported and handled more easily than Pfizer, making it easier for small hospitals and rural areas to maintain.

The US Food and Drug Administration (FDA) urgently approved the Covid-19 Moderna vaccine on December 18, after receiving approval from an advisory board. 6 million doses are expected to ship this weekend. This is the second Covid-19 vaccine approved by the US.

FDA licensing helped to nearly double the Covid-19 vaccine supply in December and meet its target of vaccinating anyone in need, in the spring or summer of 2021. Moderna plans to add 20 million doses. vaccine alongside the 25 million doses of Pfizer in December.

“Moderna vaccine additions will pay off a lot,” said Claire Hannan, executive director of the Association of Immunization Managers who directs the state’s immunization efforts. The Moderna vaccine not only helps accelerate delivery of doses, but also “makes it easier to reach smaller suppliers and more rural areas,” she said.

Moderna’s vaccine, which preserves and requires easier handling, will ship in small quantities, according to US health officials. The vaccine can be stored in standard freezers. Meanwhile, Pfizer must be transported and stored in extremely cold temperatures (minus 70 degrees C), requiring dedicated freezers or dry ice, which is common only in major hospitals and urban areas. Once thawed, Moderna’s vaccine can be refrigerated for 30 days, while Pfizer is only 5 days.

Moderna’s vaccine can be shipped in containers, with a minimum of 100 doses per barrel, while Pfizer’s minimum size is 975 doses. Pfizer “poses a challenge, especially in rural areas, that large numbers of vaccines are difficult to manage,” says Anita Patel, deputy vaccine task force team deputy of the US Centers for Disease Control and Prevention (CDC), said December 10.

The technician unloads the Pfizer vaccine vials. Image: NYTimes.

“These super refrigerators are really difficult to plan, given the large numbers and the availability of vaccinations within the required timeframes,” said Rich Lakin, vaccination director at the Utah Department of Health. This has a direct effect on the doses given in hospitals, local health departments and pharmacies in the state.

Compared with the Pfizer vaccine, which costs $ 19.5 a dose, Moderna’s mRNA-1273 vaccine costs almost twice as much, at $ 37 a dose. Meanwhile, the expected price for a vaccine injection of pharmaceutical and biological firm AstraZeneca, based in the UK, is 3-4 USD.

The Cambridge-based Moderna Company, Massachusetts, says that if approved, “a majority” of its vaccines will be produced there. The Pfizer vaccine is being produced in a number of countries, including Germany and Belgium.

Both vaccines are highly effective against Covid-19 and use the same gene-based technology. Pfizer’s vaccine was 95% effective against disease in a study of 44,000 people, while Moderna’s was 91.4% effective in a study of over 30,000 people. Both vaccines have been developed and tested at unprecedented rates.

Pfizer and Moderna both asked people to come back in three or four weeks for a second dose. However, the Moderna vaccine can be injected directly into the body, while Pfizer’s must be diluted in a separate solution before vaccination.

“Moderna vaccine will help cover vaccination in Minnesota, as it is more rural. Some parts of the state may not have access to vaccines until Moderna arrives,” said Kristen Ehresmann, director of the infectious diseases division. infection of the Minnesota Department of Health, said.

The company’s supply infrastructure ensures people can access vaccines at the required temperatures, a Pfizer spokesman said. The company has improved its storage and shipping requirements, a Moderna spokesman said. This year’s stability tests have shown that vaccines can be stored at higher temperatures.

So far, the US government has signed contracts to buy 200 million doses of Moderna’s vaccine. Pfizer agreed to provide 100 million doses, although federal officials are in talks to increase the number, according to Alex Azar, Secretary of Health and Human Services, Dec. 16.

The UK has pre-ordered 7 million doses of vaccine Moderna, Canada bought 56 ​​million doses, the European Union plans to buy 160 million.

Initially, when supplies are limited, both vaccines are intended for health workers and residents of nursing homes and long-term care facilities. When more doses are available, the next expected group is essential staff such as police and teachers, the elderly and people with a background medical condition that puts a high risk of Covid-19 at risk.

Chile (According to the BBC, WSJ)


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