Uterine fibroids in transgender men using male hormones

A 30-year-old patient from Binh Duong, 6 months old, using the male hormone testosterone to prepare for transgender, discovered that his abdomen suddenly grew fast.

Doctor Nguyen Tien Minh, Head of Obstetrics and Gynecology, Nguyen Tri Phuong Hospital, Ho Chi Minh City, on December 27, said the patient came to the hospital for examination because of the rapid growth of the abdomen about 4-5 months. Patients feel heavy when walking, having difficulty eating, affecting their living.

Transgendered non-surgical patients, using testosterone for 6 months, injecting once every three weeks at a private clinic, do not periodically monitor the effects of the drug at a qualified medical facility. Before that, the patient had not had a health check. The patient stopped taking hormone supplements for about two months.

According to Dr. Minh, general abdominal ultrasound and magnetic resonance imaging (MRI) found a very large tumor in the abdomen. The tumor is too large with the risk of uterine cancer because the size increases rapidly in a short time, the doctors consult and decide to remove the fibroids and try to preserve the uterus with two appendages.

During the surgery, the surgical team discovered that the tumor was located in the front of the uterus, partially attached to the body of the uterus, so only the fibroids were removed and the uterine muscle was restored. Tumor was completely removed, weighing 2.7 kg, the size of a watermelon with a length of nearly 30 cm.

Luckily, the anatomical results showed that this was a fibroid – myometrium. After surgery, the patient recovered soon, the wound healed well and had just been discharged from the hospital.

Surgeons remove the fibroids of the uterus for the patient. Photo provided by the hospital.

Dr Minh said, fibroids – uterine muscles are very common diseases in women of reproductive age, with the age increasing gradually with age and most commonly at about 40 years old. This is an endocrine-dependent tumor in which estrogen and progesterone play a key role in development. At the time of menopause, when the amount of hormones decreases significantly, usually fibroids – uterine muscles also decrease in size. Malignancy rate is very low, but the risk of cancer if the tumor grows rapidly or grows after menopause.

“We do not have enough evidence to determine if the patient had had uterine fibroids before using testosterone. However, we found that the times during and after the testosterone injection, the fibroids of the uterus changed. The size is obvious, affecting the living conditions “, said Dr. Minh.

According to the literature, the male hormone testosterone is not a risk of fibroids – uterine muscle. However, a 13-year study by Stanford University (USA) showed that high levels of testosterone in the blood increase the risk of developing fibroids – uterine muscle.

“Before using any medicine, it is necessary to have the full examination and consultation of the doctor”, Dr. Minh recommends.

Women of reproductive age, perimenopause, and menopause should have regular gynecological examinations every year or when there are abnormal signs such as enlarged abdomen, unusual vaginal bleeding, abdominal pain or bowel movements. difficulty urination.

Le Phuong