Trials of the anti-inflammatory drug Covid-19

BrotherThe University of Oxford announces research on the anti-inflammatory drug Humira (the main active ingredient adalimumab) in the treatment of Covid-19.

On September 30, the University of Oxford announced research, showing the efforts of scientists, to want to use drugs available in the Covid-19 treatment.

The Oxford test, called AVID-CC, is specifically aimed at nursing home patients. The study is expected to attract 750 participants, across the UK.

Adalimumab active ingredient is sold under the trade name Humira, produced by the AbbVie company. This is an anti-inflammatory, anti-tumor necrosis factor. Humira is used to treat rheumatoid arthritis, Crohn’s disease, ulcerative colitis and psoriasis. Crohn’s is an inflammatory bowel disease with symptoms of abdominal pain, severe diarrhea, fatigue, weight loss and malnutrition.

This is a popular prescription drug that is readily available and affordable.

The Novartis company also produces this active ingredient, under the trade name Hymimoz.

A pedestrian walks past an illustration of a virus outside the science center in Oldham, England on August 3. Image: Reuters

Previously, studies showed that remdesivir of the pharmaceutical company Gilead, and the steroid drug dexamethasone, were effective in the treatment of Covid-19. Scientists continue to explore other anti-inflammatory drugs that may treat Covid-19. Severe infections that trigger an over-immune response are known as cytokines. Medications that block certain elements of the immune system may reduce the rapid increase in symptoms.

Nursing homes are heavily influenced by Covid-19, in many countries. If Humira is effective in treating Covid-19, it will be especially helpful in the elderly, who is most vulnerable.

Research is funded by the initiative Covid-19 Therapeutics Accelerator, is founded by the global health charity Wellcome Trust, together with the Bill & Melinda Gates Foundation and the Mastercard Impact Foundation.

As of October 1, more than one million people have died from nCoV globally as of October 1, in more than 34 million people infected. The WHO reassured the world that Covid-19 ‘could stop’. The United States is currently the worst hit country, followed by India and Brazil.

Nguyen Ngoc (Follow Reuters)


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