Do people who get enough vaccines have post-Covid-19 sequelae?

AmericaSome studies have shown that vaccines help halve the risk of post-Covid-19 sequelae, but some scientists say it is too early to draw conclusions.

Before the pandemic, Dr. David Putrino’s rehabilitation department at Mount Sinai Hospital treated about 50 patients with Parkinson’s, trauma or chronic pain each week. By the end of 2021, the number of patients increased dramatically, most of them suffering from “prolonged Covid-19”, or post-Covid-19 sequelae.

Symptoms include fatigue, shortness of breath, insomnia, joint pain, chest tightness, brain fog (memory impairment). More serious problems are damage to organs such as the kidneys, lungs, pancreas and heart. According to the World Health Organization (WHO), sequelae occur within three months of testing positive and last for at least two months.

Scientists are still trying to figure out what causes this condition. Some think that this is the result when the virus damages the body’s organ systems. Others speculate that the “prolonged Covid-19” is related to the patient’s immune response.

Dr. Putrino received about 1,600 people with sequelae after nCoV infection and there were long lines of patients waiting to be examined. Putrino found that some vaccinated people still had the condition.

“Those patients are not as many as the unvaccinated, but there are,” he said.

Vaccines can prevent or reduce the severity of Covid-19 for a long time. However, experts have not yet come to a final conclusion.

An elderly man receives a Covid-19 vaccine at the vaccination center of the Red Cross in Termini, Rome, Italy, on November 24. Photo: Reuters

The latest research by Israeli scientists shows that fully vaccinated people have a lower risk of prolonged Covid-19 infection. Experts surveyed 950 F0 at a number of hospitals from March 2020 to June 2021. In which, 67% of people surveyed were vaccinated.

They found that fully vaccinated people were 54-68% less likely to experience post-Covid-19 sequelae between 4 and 11 months from symptom onset.

“Our results show that in addition to reducing the risk of acute illness, two doses of the vaccine also provide long-term protection against Covid-19,” said lead researcher Dr Paul Kuodi, from Bar-Ilan University. .

This result is consistent with previous research at Imperial College London, published in the journal Lancet in September 2021. The experts also said that people who received the Pfizer, Moderna and AstraZeneca vaccines were less likely to experience sequelae than those who were not vaccinated. “We found that the rate of sequelae for 28 days or longer was halved after two doses of the vaccine,” the report states.

The study was based on medical data of F0s from December 2020 to July 2021. In which, more than 6,000 cases of nCoV infection broke out after the first dose, more than 2,300 people contracted Covid-19 after the second dose.

However, until now, scientists have not come to definite conclusions. The results of the studies are also inconsistent. For example, in a report by a team of experts at the University of Oxford, there was no discernible difference in the prolonged incidence of Covid-19 before and after vaccination.

The study was conducted on 9,400 patients, vaccinated with Pfizer Moderna or Johnson & Johnson. Scientists also found that in people over 60 years old infected with breakthrough nCoV, the vaccine’s ability to protect against sequelae is almost zero. They described this as “worrying”.

Currently, experts and health officials are still controversial when it comes to the longevity of Covid-19 and vaccination status. While vaccines can significantly reduce severe symptoms, they may not completely prevent sequelae. The country with a high vaccination rate still records many persistent Covid-19 cases.

Thuc Linh (Follow Nature, SCMP)


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